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Combing Immunoinformatics with Pangenome Analysis To Design a Multiepitope Subunit Vaccine against Klebsiella pneumoniae K1, K2, K47, and K64

Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a leading causative agent of nosocomial infections, mainly infecting patients with immunosuppressive diseases. Capsular (K) serotypes K1, K2, K47, and K64 are commonly associated with higher virulence (hypervirulent Kl...

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Detalles Bibliográficos
Autores principales: Wang, Zhuohao, Guo, Genglin, Li, Quan, Li, Pei, Li, Min, Zhou, Lu, Tan, Zhongming, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431259/
https://www.ncbi.nlm.nih.gov/pubmed/35863000
http://dx.doi.org/10.1128/spectrum.01148-22