Human Air-Liquid-Interface Organotypic Airway Cultures Express Significantly More ACE2 Receptor Protein and Are More Susceptible to HCoV-NL63 Infection than Monolayer Cultures of Primary Respiratory Epithelial Cells

Human coronavirus NL63 (HCoV-NL63) is commonly associated with mild respiratory tract infections in infants, being that the respiratory epithelial cells are the main target for infection and initial replication of this virus. Standard immortalized cells are highly permissive to HCoV-NL63, and they a...

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Detalles Bibliográficos
Autores principales: Castillo, Gino, Mora-Díaz, Juan Carlos, Nelli, Rahul K., Giménez-Lirola, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431431/
https://www.ncbi.nlm.nih.gov/pubmed/35863002
http://dx.doi.org/10.1128/spectrum.01639-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431431/
https://www.ncbi.nlm.nih.gov/pubmed/35863002
http://dx.doi.org/10.1128/spectrum.01639-22

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