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Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans

A balance in the deoxyribonucleotide (dNTPs) intracellular concentration is critical for the DNA replication and repair processes. In the model yeast Saccharomyces cerevisiae, the Mec1-Rad53-Dun1 kinase cascade mainly regulates the ribonucleotide reductase (RNR) gene expression during DNA replicatio...

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Detalles Bibliográficos
Autores principales: Jung, Kwang-Woo, Kwon, Sunhak, Jung, Jong-Hyun, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431586/
https://www.ncbi.nlm.nih.gov/pubmed/35736239
http://dx.doi.org/10.1128/spectrum.01044-22