Cargando…

Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans

A balance in the deoxyribonucleotide (dNTPs) intracellular concentration is critical for the DNA replication and repair processes. In the model yeast Saccharomyces cerevisiae, the Mec1-Rad53-Dun1 kinase cascade mainly regulates the ribonucleotide reductase (RNR) gene expression during DNA replicatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jung, Kwang-Woo, Kwon, Sunhak, Jung, Jong-Hyun, Bahn, Yong-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431586/ https://www.ncbi.nlm.nih.gov/pubmed/35736239 http://dx.doi.org/10.1128/spectrum.01044-22

Ejemplares similares

Essential Roles of the Kar2/BiP Molecular Chaperone Downstream of the UPR Pathway in Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2013)

Functional Roles of Homologous Recombination and Non-Homologous End Joining in DNA Damage Response and Microevolution in Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2021)

The Stress-Activated Signaling (SAS) Pathways of a Human Fungal Pathogen, Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2009)

Functional Characterization of cAMP-Regulated Gene, CAR1, in Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2010)

A Case of Pulmonary Cryptococcosis by Capsule-deficient Cryptococcus neoformans
por: Cheon, Won Seok, et al.
Publicado: (2006)

Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
por: Lee, Kyung-Tae, et al.
Publicado: (2020)

The capsule of Cryptococcus neoformans
por: Casadevall, Arturo, et al.
Publicado: (2018)

The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans
por: Wang, Li Li, et al.
Publicado: (2018)

Ribonucleotide reductases: essential enzymes for bacterial life
por: Torrents, Eduard
Publicado: (2014)

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
por: Lee, Kyung-Tae, et al.
Publicado: (2016)

Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans
por: Cheon, Seon Ah, et al.
Publicado: (2011)

Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans
por: Lee, Dongpil, et al.
Publicado: (2019)

Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2016)

Mechanisms of Cryptococcus neoformans-Mediated Host Damage
por: Casadevall, Arturo, et al.
Publicado: (2018)

Modulation of Replicative Lifespan in Cryptococcus neoformans: Implications for Virulence
por: Bouklas, Tejas, et al.
Publicado: (2017)

Investigation of Antifungal Mechanisms of Thymol in the Human Fungal Pathogen, Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2021)

Unraveling Capsule Biosynthesis and Signaling Networks in Cryptococcus neoformans
por: Jang, Eun-Ha, et al.
Publicado: (2022)

Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
por: Foskolou, Iosifina P., et al.
Publicado: (2017)

Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans
por: Son, Ye-Eun, et al.
Publicado: (2018)

Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans
por: Kim, Hanhae, et al.
Publicado: (2015)

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2015)

Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans
por: Kim, Jin-Young, et al.
Publicado: (2022)

Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans
por: Kim, Seo-Young, et al.
Publicado: (2011)

Cryptococcus neoformans STE12α Regulates Virulence but Is Not Essential for Mating
por: Chang, Y.C., et al.
Publicado: (2000)

etymologia: Cryptococcus neoformans
Publicado: (2008)

Fluconazole induces ROS in Cryptococcus neoformans and contributes to DNA damage in vitro
por: Peng, Congyue Annie, et al.
Publicado: (2018)

Regulation of Small Mitochondrial DNA Replicative Advantage by Ribonucleotide Reductase in Saccharomyces cerevisiae
por: Bradshaw, Elliot, et al.
Publicado: (2017)

Influence of Iron Regulation on the Metabolome of Cryptococcus neoformans
por: Choi, Jung Nam, et al.
Publicado: (2012)

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
por: Jin, Jae-Hyung, et al.
Publicado: (2020)

Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target
por: Ruma, Yasmeen N., et al.
Publicado: (2022)

Intron retention-dependent gene regulation in Cryptococcus neoformans
por: Gonzalez-Hilarion, Sara, et al.
Publicado: (2016)

Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
por: Esher, Shannon K., et al.
Publicado: (2016)

Convergent allostery in ribonucleotide reductase
por: Thomas, William C., et al.
Publicado: (2019)

The periodic table of ribonucleotide reductases
por: Ruskoski, Terry B., et al.
Publicado: (2021)

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans
por: Boyce, Kylie J., et al.
Publicado: (2017)

Antifungal Susceptibilities of Cryptococcus neoformans
por: Archibald, Lennox K., et al.
Publicado: (2004)

Environmental Status of Cryptococcus neoformans and Cryptococcus gattii in Colombia
por: Serna-Espinosa, Briggith-Nathalia, et al.
Publicado: (2021)

A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans
por: Cheon, Seon Ah, et al.
Publicado: (2017)

Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
por: Thak, Eun Jung, et al.
Publicado: (2020)

Antifungal and Anti-Biofilm Activity of Essential Oil Active Components against Cryptococcus neoformans and Cryptococcus laurentii
por: Kumari, Poonam, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a7mgek1mjh38ha7rhfjpgoohue