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Discordance between HIV-1 Population in Plasma at Rebound after Structured Treatment Interruption and Archived Provirus Population in Peripheral Blood Mononuclear Cells

Antiretroviral therapy (ART) can sustain the suppression of plasma viremia to below detection levels. Infected individuals undergoing a treatment interruption exhibit rapid viral rebound in plasma viremia which is fueled by cellular reservoirs such as CD4(+) T cells, myeloid cells, and potentially u...

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Detalles Bibliográficos
Autores principales: Hendricks, Chynna M., Cash, Melanie N., Tagliamonte, Massimiliano S., Riva, Alberto, Brander, Christian, Llano, Anuska, Salemi, Marco, Stevenson, Mario, Mavian, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431602/
https://www.ncbi.nlm.nih.gov/pubmed/35699458
http://dx.doi.org/10.1128/spectrum.01353-22