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Genotypic and Phenotypic Diversity of the Replication-Competent HIV Reservoir in Treated Patients

In HIV infection, viral rebound after treatment discontinuation is considered to originate predominantly from viral genomes integrated in resting CD4(+) T lymphocytes. Replication-competent proviral genomes represent a minority of the total HIV DNA. While the quantification of the HIV reservoir has...

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Detalles Bibliográficos
Autores principales: Nicolas, Alexandre, Migraine, Julie, Dutrieux, Jacques, Salmona, Maud, Tauzin, Alexandra, Hachiya, Atsuko, Estaquier, Jérôme, Molina, Jean-Michel, Clavel, François, Hance, Allan J., Mammano, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431663/
https://www.ncbi.nlm.nih.gov/pubmed/35770985
http://dx.doi.org/10.1128/spectrum.00784-22