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Genotypic and Phenotypic Diversity of the Replication-Competent HIV Reservoir in Treated Patients
In HIV infection, viral rebound after treatment discontinuation is considered to originate predominantly from viral genomes integrated in resting CD4(+) T lymphocytes. Replication-competent proviral genomes represent a minority of the total HIV DNA. While the quantification of the HIV reservoir has...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431663/ https://www.ncbi.nlm.nih.gov/pubmed/35770985 http://dx.doi.org/10.1128/spectrum.00784-22 |