Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of α′-Mycolic Acids

Mycolic acids, a hallmark of the genus Mycobacterium, are unique branched long-chain fatty acids produced by a complex biosynthetic pathway. Due to their essentiality and involvement in various aspects of mycobacterial pathogenesis, the synthesis of mycolic acids—and the identification of the enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Capua, Cecilia B., Belardinelli, Juan M., Carignano, Hugo A., Buchieri, María V., Suarez, Cristian A., Morbidoni, Héctor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431677/
https://www.ncbi.nlm.nih.gov/pubmed/35862962
http://dx.doi.org/10.1128/spectrum.01288-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431677/
https://www.ncbi.nlm.nih.gov/pubmed/35862962
http://dx.doi.org/10.1128/spectrum.01288-22

Ejemplares similares