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A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve

Membrane instability and disruption underlie myriad acute and chronic disorders. Anxa6 encodes the membrane-associated protein annexin A6 and was identified as a genetic modifier of muscle repair and muscular dystrophy. To evaluate annexin A6’s role in membrane repair in vivo, we inserted sequences...

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Detalles Bibliográficos
Autores principales: Demonbreun, Alexis R., Bogdanovic, Elena, Vaught, Lauren A., Reiser, Nina L., Fallon, Katherine S., Long, Ashlee M., Oosterbaan, Claire C., Hadhazy, Michele, Page, Patrick G.T., Joseph, Prem Raj B., Cowen, Gabrielle, Telenson, Alexander M., Khatri, Ammaarah, Sadleir, Katherine R., Vassar, Robert, McNally, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431694/
https://www.ncbi.nlm.nih.gov/pubmed/35866481
http://dx.doi.org/10.1172/jci.insight.158107