EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia

Blood clot formation initiates ischemic events, but coagulation roles during postischemic tissue repair are poorly understood. The endothelial protein C receptor (EPCR) regulates coagulation, as well as immune and vascular signaling, by protease activated receptors (PARs). Here, we show that endothe...

Descripción completa

Detalles Bibliográficos
Autores principales: Bochenek, Magdalena L., Gogiraju, Rajinikanth, Großmann, Stefanie, Krug, Janina, Orth, Jennifer, Reyda, Sabine, Georgiadis, George S., Spronk, Henri M., Konstantinides, Stavros, Münzel, Thomas, Griffin, John H., Wild, Philipp, Espinola-Klein, Christine, Ruf, Wolfram, Schäfer, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431695/
https://www.ncbi.nlm.nih.gov/pubmed/35700057
http://dx.doi.org/10.1172/jci.insight.157701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431695/
https://www.ncbi.nlm.nih.gov/pubmed/35700057
http://dx.doi.org/10.1172/jci.insight.157701

Ejemplares similares