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EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia

Blood clot formation initiates ischemic events, but coagulation roles during postischemic tissue repair are poorly understood. The endothelial protein C receptor (EPCR) regulates coagulation, as well as immune and vascular signaling, by protease activated receptors (PARs). Here, we show that endothe...

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Detalles Bibliográficos
Autores principales:	Bochenek, Magdalena L., Gogiraju, Rajinikanth, Großmann, Stefanie, Krug, Janina, Orth, Jennifer, Reyda, Sabine, Georgiadis, George S., Spronk, Henri M., Konstantinides, Stavros, Münzel, Thomas, Griffin, John H., Wild, Philipp, Espinola-Klein, Christine, Ruf, Wolfram, Schäfer, Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431695/ https://www.ncbi.nlm.nih.gov/pubmed/35700057 http://dx.doi.org/10.1172/jci.insight.157701

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