PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils

Acute lung injury (ALI) can cause acute respiratory distress syndrome (ARDS), a lethal condition with limited treatment options and currently a common global cause of death due to COVID-19. ARDS secondary to transfusion-related ALI (TRALI) has been recapitulated preclinically by anti–MHC-I antibody...

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Detalles Bibliográficos
Autores principales: Song, Dongyan, Adrover, Jose M., Felice, Christy, Christensen, Lisa N., He, Xue-Yan, Merrill, Joseph R., Wilkinson, John E., Janowitz, Tobias, Lyons, Scott K., Egeblad, Mikala, Tonks, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431713/
https://www.ncbi.nlm.nih.gov/pubmed/35866483
http://dx.doi.org/10.1172/jci.insight.158199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431713/
https://www.ncbi.nlm.nih.gov/pubmed/35866483
http://dx.doi.org/10.1172/jci.insight.158199

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