Cargando…

PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils

Acute lung injury (ALI) can cause acute respiratory distress syndrome (ARDS), a lethal condition with limited treatment options and currently a common global cause of death due to COVID-19. ARDS secondary to transfusion-related ALI (TRALI) has been recapitulated preclinically by anti–MHC-I antibody...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Dongyan, Adrover, Jose M., Felice, Christy, Christensen, Lisa N., He, Xue-Yan, Merrill, Joseph R., Wilkinson, John E., Janowitz, Tobias, Lyons, Scott K., Egeblad, Mikala, Tonks, Nicholas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431713/ https://www.ncbi.nlm.nih.gov/pubmed/35866483 http://dx.doi.org/10.1172/jci.insight.158199

Ejemplares similares

Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection
por: Adrover, Jose M., et al.
Publicado: (2022)

PTP1B: mediating ROS signaling to silence genes
por: Boivin, Benoit, et al.
Publicado: (2015)

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series
por: Weber, Andrew G., et al.
Publicado: (2020)

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series
por: Weber, Andrew G., et al.
Publicado: (2020)

Dynamic Interaction of PTPμ with Multiple Cadherins In Vivo
por: Brady-Kalnay, Susann M., et al.
Publicado: (1998)

Targeting the disordered C-terminus of PTP1B with an allosteric inhibitor
por: Krishnan, Navasona, et al.
Publicado: (2014)

Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks
por: Bonham, Christopher A., et al.
Publicado: (2023)

Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development
por: Krishnan, Navasona, et al.
Publicado: (2018)

Caught in the act: revealing the metastatic process by live imaging
por: Fein, Miriam R., et al.
Publicado: (2013)

Isolation of mouse mammary carcinoma-derived macrophages and cancer cells for co-culture assays
por: Sun, Lijuan, et al.
Publicado: (2022)

Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer
por: Nakasone, Elizabeth S., et al.
Publicado: (2013)

Regulation of PTP1B activation through disruption of redox-complex formation
por: Londhe, Avinash D., et al.
Publicado: (2019)

PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity
por: Wiede, Florian, et al.
Publicado: (2022)

DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease
por: Krishnan, Navasona, et al.
Publicado: (2018)

System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
por: Rajaram, Megha, et al.
Publicado: (2013)

Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
por: Watanabe, Koji, et al.
Publicado: (2017)

PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
por: Yue, Lei, et al.
Publicado: (2019)

Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration
por: Hu, Nan, et al.
Publicado: (2011)

Targeting potential drivers of COVID-19: Neutrophil extracellular traps
por: Barnes, Betsy J., et al.
Publicado: (2020)

Targeting VE-PTP phosphatase protects the kidney from diabetic injury
por: Carota, Isabel A., et al.
Publicado: (2019)

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase
por: Gong, Lei, et al.
Publicado: (2013)

CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
por: Mattos, Matheus Silverio, et al.
Publicado: (2020)

Vanadium Compounds as PTP Inhibitors
por: Irving, Elsa, et al.
Publicado: (2017)

Presence of Insulin-Like Growth Factor Binding Proteins Correlates With Tumor-Promoting Effects of Matrix Metalloproteinase 9 in Breast Cancer()()
por: Park, Jae-Hyun, et al.
Publicado: (2015)

CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet–Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
por: Ngamsri, Kristian-Christos, et al.
Publicado: (2021)

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR
por: Emperador-Melero, Javier, et al.
Publicado: (2021)

Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation
por: Ngamsri, Kristian-Christos, et al.
Publicado: (2020)

Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis
por: Khaw, Yee Ming, et al.
Publicado: (2020)

CXCR4, the master regulator of neutrophil trafficking in homeostasis and disease
por: De Filippo, Katia, et al.
Publicado: (2018)

CXCR2 intrinsically drives the maturation and function of neutrophils in mice
por: Delobel, Pauline, et al.
Publicado: (2022)

CXCR4(hi) effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4(hi) neutrophil polarization
por: Garcia, Flavia, et al.
Publicado: (2020)

TC-PTP nuclear trafficking in keratinocytes
por: Kim, Mihwa, et al.
Publicado: (2017)

CXCR5+ CD8 T Cells: Protective or Pathogenic?
por: Valentine, Kristen M., et al.
Publicado: (2019)

HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε Activation
por: Mancardi, Daniele, et al.
Publicado: (2022)

Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response
por: Merrill, Joseph R., et al.
Publicado: (2023)

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
por: Walsh, Carolyn M, et al.
Publicado: (2019)

Mechanisms of PTPσ-Mediated Presynaptic Differentiation
por: Bomkamp, Claire, et al.
Publicado: (2019)

n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils
por: Wu, Beibei, et al.
Publicado: (2018)

Dual PTP1B/TC-PTP Inhibitors: Biological Evaluation of 3-(Hydroxymethyl)cinnoline-4(1H)-Ones
por: Derkach, Kira V., et al.
Publicado: (2023)

Circadian Features of Neutrophil Biology
por: Aroca-Crevillén, Alejandra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nenga82h2sdjev3cnkriifobe4