Cargando…

The intrinsic and extrinsic effects of TET proteins during gastrulation

Mice deficient for all ten-eleven translocation (TET) genes exhibit early gastrulation lethality. However, separating cause and effect in such embryonic failure is challenging. To isolate cell-autonomous effects of TET loss, we used temporal single-cell atlases from embryos with partial or complete...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Saifeng, Mittnenzweig, Markus, Mayshar, Yoav, Lifshitz, Aviezer, Dunjić, Marko, Rais, Yoach, Ben-Yair, Raz, Gehrs, Stephanie, Chomsky, Elad, Mukamel, Zohar, Rubinstein, Hernan, Schlereth, Katharina, Reines, Netta, Orenbuch, Ayelet-Hashahar, Tanay, Amos, Stelzer, Yonatan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432429/
https://www.ncbi.nlm.nih.gov/pubmed/35908548
http://dx.doi.org/10.1016/j.cell.2022.06.049