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The intrinsic and extrinsic effects of TET proteins during gastrulation
Mice deficient for all ten-eleven translocation (TET) genes exhibit early gastrulation lethality. However, separating cause and effect in such embryonic failure is challenging. To isolate cell-autonomous effects of TET loss, we used temporal single-cell atlases from embryos with partial or complete...
Autores principales: | Cheng, Saifeng, Mittnenzweig, Markus, Mayshar, Yoav, Lifshitz, Aviezer, Dunjić, Marko, Rais, Yoach, Ben-Yair, Raz, Gehrs, Stephanie, Chomsky, Elad, Mukamel, Zohar, Rubinstein, Hernan, Schlereth, Katharina, Reines, Netta, Orenbuch, Ayelet-Hashahar, Tanay, Amos, Stelzer, Yonatan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432429/ https://www.ncbi.nlm.nih.gov/pubmed/35908548 http://dx.doi.org/10.1016/j.cell.2022.06.049 |
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