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Packaging, Purification, and Titration of Replication-Deficient Semliki Forest Virus-Derived Particles as a Self-Amplifying mRNA Vaccine Vector

BACKGROUND: Self-amplifying mRNA is the next-generation vaccine platform with the potential advantages in efficacy and speed of development against infectious diseases and cancer. The main aim was to present optimized and rapid methods for SFV-PD SAM preparation, its packaging, and titer determinati...

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Detalles Bibliográficos
Autores principales: Savar, Nastaran Sadat, Vallet, Thomas, Arashkia, Arash, Lundstrom, Kenneth, Vignuzzi, Marco, Mahmoudzadeh Niknam, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432467/
https://www.ncbi.nlm.nih.gov/pubmed/35468712
http://dx.doi.org/10.52547/ibj.3535