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The role of the platelet pool of Plasminogen Activator Inhibitor-1 in well-controlled type 2 diabetes patients

BACKGROUND: The main inhibitor of the fibrinolytic system, Plasminogen Activator Inhibitor -1 (PAI-1), irreversibly binds tissue-type Plasminogen Activator (t-PA) and thereby inhibits the protective action of tPA against thrombus formation. Elevated levels of plasma PAI-1 are associated with an incr...

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Detalles Bibliográficos
Autores principales: Mossberg, Karin, Olausson, Josefin, Fryk, Emanuel, Jern, Sverker, Jansson, Per-Anders, Brogren, Helén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432754/
https://www.ncbi.nlm.nih.gov/pubmed/36044519
http://dx.doi.org/10.1371/journal.pone.0267833