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Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases

Mycobacterium tuberculosis adenylyl cyclase (AC) Rv1625c/Cya is an evolutionary ancestor of the mammalian membrane ACs and a model system for studies of their structure and function. Although the vital role of ACs in cellular signalling is well established, the function of their transmembrane (TM) r...

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Detalles Bibliográficos
Autores principales: Mehta, Ved, Khanppnavar, Basavraj, Schuster, Dina, Kantarci, Ilayda, Vercellino, Irene, Kosturanova, Angela, Iype, Tarun, Stefanic, Sasa, Picotti, Paola, Korkhov, Volodymyr M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433096/
https://www.ncbi.nlm.nih.gov/pubmed/35980026
http://dx.doi.org/10.7554/eLife.77032