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Goblet cells need some stress

The intestinal tract is protected by epithelium-covering mucus, which is constantly renewed by goblet cells, a specialized type of epithelial cell. Mucus is largely composed of MUC2 mucin, an enormous molecule that poses a high demand on the endoplasmic reticulum (ER) for proper folding and protein...

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Detalles Bibliográficos
Autores principales: Johansson, Malin E.V., Hansson, Gunnar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433097/
https://www.ncbi.nlm.nih.gov/pubmed/36047499
http://dx.doi.org/10.1172/JCI162030