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Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
The switch from anchorage-dependent to anchorage-independent growth is essential for epithelial metastasis. The underlying mechanism, however, is not fully understood. In this study, we identified growth factor independent-1 (GFI1), a transcription factor that drives the transition from adherent end...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433100/ https://www.ncbi.nlm.nih.gov/pubmed/35819844 http://dx.doi.org/10.1172/JCI149551 |