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Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells

The switch from anchorage-dependent to anchorage-independent growth is essential for epithelial metastasis. The underlying mechanism, however, is not fully understood. In this study, we identified growth factor independent-1 (GFI1), a transcription factor that drives the transition from adherent end...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Lin, Zhenzhen, Nian, Zhe, Zhang, Wei, Liu, Wenxu, Yan, Fei, Xiao, Zengtuan, Wang, Xia, Zhang, Zhenfa, Ma, Zhenyi, Liu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433100/
https://www.ncbi.nlm.nih.gov/pubmed/35819844
http://dx.doi.org/10.1172/JCI149551