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Tetracycline-induced mitohormesis mediates disease tolerance against influenza

Mitohormesis defines the increase in fitness mediated by adaptive responses to mild mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on eukaryotic cells. We demonstrate in cell and germ-free mouse mod...

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Detalles Bibliográficos
Autores principales: Mottis, Adrienne, Li, Terytty Y., El Alam, Gaby, Rapin, Alexis, Katsyuba, Elena, Liaskos, David, D’Amico, Davide, Harris, Nicola L., Grier, Mark C., Mouchiroud, Laurent, Nelson, Mark L., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433105/
https://www.ncbi.nlm.nih.gov/pubmed/35787521
http://dx.doi.org/10.1172/JCI151540