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Tetracycline-induced mitohormesis mediates disease tolerance against influenza
Mitohormesis defines the increase in fitness mediated by adaptive responses to mild mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on eukaryotic cells. We demonstrate in cell and germ-free mouse mod...
Autores principales: | Mottis, Adrienne, Li, Terytty Y., El Alam, Gaby, Rapin, Alexis, Katsyuba, Elena, Liaskos, David, D’Amico, Davide, Harris, Nicola L., Grier, Mark C., Mouchiroud, Laurent, Nelson, Mark L., Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433105/ https://www.ncbi.nlm.nih.gov/pubmed/35787521 http://dx.doi.org/10.1172/JCI151540 |
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