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Astrocytic IGF-1 and IGF-1R Orchestrate Mitophagy in Traumatic Brain Injury via Exosomal miR-let-7e

Defective brain hormonal signaling and autophagy have been associated with neurodegeneration after brain insults, characterized by neuronal loss and cognitive dysfunction. However, few studies have linked them in the context of brain injury. Insulin-like growth factor-1 (IGF-1) is an important hormo...

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Detalles Bibliográficos
Autores principales: Dabin, Ren, Wei, Chen, Liang, Shu, Ke, Cao, Zhihan, Wang, Ping, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433209/
https://www.ncbi.nlm.nih.gov/pubmed/36062186
http://dx.doi.org/10.1155/2022/3504279