Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats

BACKGROUND: Hyperandrogenism is a common characteristic of polycystic ovary syndrome (PCOS). Long-term, continuous exposure to hyperandrogenic environments may cause excessive endoplasmic reticulum (ER) stress in ovarian granulosa cells (GCs). Curcumin is a polyphenol extracted from turmeric rhizome...

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Detalles Bibliográficos
Autores principales: Zhang, Yaling, Wang, Lei, Weng, Yajing, Wang, Daojuan, Wang, Rong, Wang, Hongwei, Wang, Lihui, Shen, Shanmei, Li, Yan, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433213/
https://www.ncbi.nlm.nih.gov/pubmed/36062194
http://dx.doi.org/10.1155/2022/2113293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433213/
https://www.ncbi.nlm.nih.gov/pubmed/36062194
http://dx.doi.org/10.1155/2022/2113293

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