Silencing RNA for MMPs May Be Utilized for Cardioprotection

Ischemia/reperfusion (I/R) injury is accompanied by an increase of matrix metalloproteinase 2 (MMP-2) activity, which degrades heart contractile proteins. The aim of the study was to investigate the effect of MMP-2 small interfering RNA (MMP-2 siRNA) administration on I/R heart. Isolated rat hearts...

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Detalles Bibliográficos
Autores principales: Banaszkiewicz, Marta, Krzywonos-Zawadzka, Anna, Olejnik, Agnieszka, Noszczyk-Nowak, Agnieszka, Bil-Lula, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433229/
https://www.ncbi.nlm.nih.gov/pubmed/36082193
http://dx.doi.org/10.1155/2022/9729018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433229/
https://www.ncbi.nlm.nih.gov/pubmed/36082193
http://dx.doi.org/10.1155/2022/9729018

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