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Endocytosis in the axon initial segment maintains neuronal polarity

Neurons are highly polarized cells that face the fundamental challenge of compartmentalizing a vast and diverse repertoire of proteins in order to function properly(1). The axon initial segment (AIS) is a specialized domain that separates a neuron’s morphologically, biochemically and functionally di...

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Detalles Bibliográficos
Autores principales: Eichel, Kelsie, Uenaka, Takeshi, Belapurkar, Vivek, Lu, Rui, Cheng, Shouqiang, Pak, Joseph S., Taylor, Caitlin A., Südhof, Thomas C., Malenka, Robert, Wernig, Marius, Özkan, Engin, Perrais, David, Shen, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433327/
https://www.ncbi.nlm.nih.gov/pubmed/35978188
http://dx.doi.org/10.1038/s41586-022-05074-5