Cargando…

Endocytosis in the axon initial segment maintains neuronal polarity

Neurons are highly polarized cells that face the fundamental challenge of compartmentalizing a vast and diverse repertoire of proteins in order to function properly(1). The axon initial segment (AIS) is a specialized domain that separates a neuron’s morphologically, biochemically and functionally di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eichel, Kelsie, Uenaka, Takeshi, Belapurkar, Vivek, Lu, Rui, Cheng, Shouqiang, Pak, Joseph S., Taylor, Caitlin A., Südhof, Thomas C., Malenka, Robert, Wernig, Marius, Özkan, Engin, Perrais, David, Shen, Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433327/ https://www.ncbi.nlm.nih.gov/pubmed/35978188 http://dx.doi.org/10.1038/s41586-022-05074-5

Ejemplares similares

Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation
por: Patzke, Christopher, et al.
Publicado: (2016)

No endocytosis in the axonal entry
por: LeBrasseur, Nicole
Publicado: (2004)

NuMA1 promotes axon initial segment assembly through inhibition of endocytosis
por: Torii, Tomohiro, et al.
Publicado: (2019)

Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles
por: Bacaj, Taulant, et al.
Publicado: (2015)

Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane
por: Kleine-Vehn, Jürgen, et al.
Publicado: (2011)

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis
por: Taylor, Marcus J., et al.
Publicado: (2011)

pHuji, a pH-sensitive red fluorescent protein for imaging of exo- and endocytosis
por: Shen, Yi, et al.
Publicado: (2014)

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity
por: Hedstrom, Kristian L., et al.
Publicado: (2008)

Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity
por: Jones, Steven L., et al.
Publicado: (2016)

Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking
por: Chanda, Soham, et al.
Publicado: (2015)

Synaptogenic effect of APP-Swedish mutation in familial Alzheimer’s disease
por: Zhou, Bo, et al.
Publicado: (2022)

Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment
por: Abouelezz, Amr, et al.
Publicado: (2020)

Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis
por: Drews, Kelly, et al.
Publicado: (2019)

NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance
por: Pak, Joseph S., et al.
Publicado: (2020)

NgCAM and VAMP2 reveal that direct delivery and dendritic degradation maintain axonal polarity
por: Nabb, Alec T., et al.
Publicado: (2022)

Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis
por: Martineau, Magalie, et al.
Publicado: (2017)

Polarization of endocytosis and receptor topography on cultured macrophages
Publicado: (1980)

Formin Activity and mDia1 Contribute to Maintain Axon Initial Segment Composition and Structure
por: Zhang, Wei, et al.
Publicado: (2021)

Direct conversion of fibroblasts to functional neurons by defined factors
por: Vierbuchen, Thomas, et al.
Publicado: (2010)

Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis
por: Rosendale, Morgane, et al.
Publicado: (2019)

A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors
por: Bhattacharyya, Samarjit, et al.
Publicado: (2009)

Clathrin-independent endocytosis, retrograde trafficking, and cell polarity
por: Shafaq-Zadah, Massiullah, et al.
Publicado: (2020)

Functional Conservation of Cis-Regulatory Elements of Heat-Shock Genes over Long Evolutionary Distances
por: He, Zhengying, et al.
Publicado: (2011)

Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors
por: Wang, Jing, et al.
Publicado: (2021)

SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function
por: Ribeiro, Luís F., et al.
Publicado: (2019)

Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport
Publicado: (1993)

Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing
por: Niederst, Emily D., et al.
Publicado: (2015)

Polarity orientation of axonal microtubules
Publicado: (1981)

Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1
por: Chanda, Soham, et al.
Publicado: (2014)

Sandra Schmid: Collaring endocytosis
por: Sedwick, Caitlin
Publicado: (2010)

Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics
por: Ng, Yi Han, et al.
Publicado: (2021)

Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells
Publicado: (1986)

THE AXON HILLOCK AND THE INITIAL SEGMENT
por: Palay, Sanford L., et al.
Publicado: (1968)

Wrapping Our Heads around Endocytosis
por: Sedwick, Caitlin
Publicado: (2009)

Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis
por: Paul, David, et al.
Publicado: (2023)

How neurons maintain their axons long-term: an integrated view of axon biology and pathology
por: Smith, Gaynor, et al.
Publicado: (2023)

Mitochondrial Structure and Polarity in Dendrites and the Axon Initial Segment Are Regulated by Homeostatic Plasticity and Dysregulated in Fragile X Syndrome
por: Bülow, Pernille, et al.
Publicado: (2021)

Clathrin-mediated endocytosis regulates fMLP-mediated neutrophil polarization
por: Tan, Xinyu, et al.
Publicado: (2018)

Autophagic degradation of CNS myelin maintains axon integrity
por: Ktena, Niki, et al.
Publicado: (2022)

Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment
por: Pan-Vazquez, Alejandro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t1b2g2ttqprg1d3c1k5k60cni3