Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis

Hierarchical organization of intestine relies on the self-renewal and tightly regulated differentiation of intestinal stem cells (ISCs). Although signals like Wnt are known to sustain the continued intestinal renewal by maintaining ISCs activity and lineage commitment, molecular mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Fan, Yujia, Huo, Xiaohan, Guo, Beibei, Zhang, Xiaohui, Yang, Yang, Lian, Jiabei, Meng, Xinyuan, Shao, Yiwen, Zou, Yongxin, Guo, Haiyang, Wang, Haitao, Sun, Gongping, Dou, Hao, Wang, Jinshen, Shao, Changshun, Gong, Yaoqin, Hu, Huili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433385/
https://www.ncbi.nlm.nih.gov/pubmed/35197566
http://dx.doi.org/10.1038/s41418-022-00954-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433385/
https://www.ncbi.nlm.nih.gov/pubmed/35197566
http://dx.doi.org/10.1038/s41418-022-00954-9

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