Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration

Atrophic (“dry”) form of age-related macular degeneration (AMD) is a leading cause of vision loss characterized by macular retinal pigment epithelium (RPE) and the ensuing photoreceptor degeneration. cGAS-STING signaling is a key cytosolic DNA sensor system in innate immunity and have recently been...

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Detalles Bibliográficos
Autores principales: Zou, Ming, Ke, Qin, Nie, Qian, Qi, Ruili, Zhu, Xingfei, Liu, Wei, Hu, Xuebin, Sun, Qian, Fu, Jia-Ling, Tang, Xiangcheng, Liu, Yizhi, Li, David Wan-Cheng, Gong, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433402/
https://www.ncbi.nlm.nih.gov/pubmed/35347235
http://dx.doi.org/10.1038/s41418-022-00967-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433402/
https://www.ncbi.nlm.nih.gov/pubmed/35347235
http://dx.doi.org/10.1038/s41418-022-00967-4

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