Cargando…
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F(1) subcomplex
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates during excitotoxic ischemic insult. In this present...
Autores principales: | Mnatsakanyan, Nelli, Park, Han-A, Wu, Jing, He, Xiang, Llaguno, Marc C., Latta, Maria, Miranda, Paige, Murtishi, Besnik, Graham, Morven, Weber, Joachim, Levy, Richard J., Pavlov, Evgeny V., Jonas, Elizabeth A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433415/ https://www.ncbi.nlm.nih.gov/pubmed/35322203 http://dx.doi.org/10.1038/s41418-022-00972-7 |
Ejemplares similares
-
A mitochondrial megachannel resides in monomeric F(1)F(O) ATP synthase
por: Mnatsakanyan, Nelli, et al.
Publicado: (2019) -
ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore
por: Neginskaya, Maria A., et al.
Publicado: (2019) -
Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth
por: Chen, Rongmin, et al.
Publicado: (2019) -
Postsynaptic densities fragment into subcomplexes upon sonication
por: Dosemeci, Ayse, et al.
Publicado: (2019) -
Entrapment of water by subunit c of ATP synthase
por: McGeoch, Julie E.M, et al.
Publicado: (2007)