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A STAT5-Smad3 dyad regulates adipogenic plasticity of visceral adipose mesenchymal stromal cells during chronic inflammation

Adipogenic differentiation of visceral adipose tissue-resident multipotent mesenchymal stromal cells (VA-MSC) into adipocytes is metabolically protective. Under chronic inflammatory stress, this neoadipogenesis process is suppressed by various pro-inflammatory cytokines and growth factors. However,...

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Detalles Bibliográficos
Autores principales: Das, Rahul, Giri, Jayeeta, K. Paul, Pradyut, Froelich, Nicole, Chinnadurai, Raghavan, McCoy, Sara, Bushman, Wade, Galipeau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433418/
https://www.ncbi.nlm.nih.gov/pubmed/36045134
http://dx.doi.org/10.1038/s41536-022-00244-5