Cargando…

Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis

Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the required levels of PAX9 and MSX1 during odontogenesis....

Descripción completa

Detalles Bibliográficos
Autores principales: Kaushal, Kamini, Kim, Eun-Jung, Tyagi, Apoorvi, Karapurkar, Janardhan Keshav, Haq, Saba, Jung, Han-Sung, Kim, Kye-Seong, Ramakrishna, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433428/
https://www.ncbi.nlm.nih.gov/pubmed/35273362
http://dx.doi.org/10.1038/s41418-022-00956-7