Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis

Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the required levels of PAX9 and MSX1 during odontogenesis....

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Detalles Bibliográficos
Autores principales: Kaushal, Kamini, Kim, Eun-Jung, Tyagi, Apoorvi, Karapurkar, Janardhan Keshav, Haq, Saba, Jung, Han-Sung, Kim, Kye-Seong, Ramakrishna, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433428/
https://www.ncbi.nlm.nih.gov/pubmed/35273362
http://dx.doi.org/10.1038/s41418-022-00956-7

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