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A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

Post-translational modifications, such as lysine acetylation, regulate the activity of diverse proteins across many cellular compartments. Protein deacetylation in mitochondria is catalyzed by the enzymatic activity of the NAD(+)-dependent deacetylase sirtuin 3 (SIRT3), however it remains unclear wh...

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Detalles Bibliográficos
Autores principales: Boutoual, Rachid, Jo, Hyunsun, Heckenbach, Indra, Tiwari, Ritesh, Kasler, Herbert, Lerner, Chad A., Shah, Samah, Schilling, Birgit, Calvanese, Vincenzo, Rardin, Matthew J., Scheibye-Knudsen, Morten, Verdin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433433/
https://www.ncbi.nlm.nih.gov/pubmed/36045139
http://dx.doi.org/10.1038/s41598-022-18114-x