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Structural basis of ion uptake in copper-transporting P(1B)-type ATPases
Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type (P(1B)-) ATPases are present in all kingdoms of life, facilitating cellular export of transition metals including copper. P-type ATPases follow an alternating access mechanism, with inward-facing E1 and outwa...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433437/ https://www.ncbi.nlm.nih.gov/pubmed/36045128 http://dx.doi.org/10.1038/s41467-022-32751-w |