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Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism

Macrophage infiltration and polarization have been increasingly observed in intervertebral disc (IVD) degeneration (IDD). However, their biological roles in IDD are still unrevealed. We harvested conditioned media (CM) derived from a spectrum of macrophages induced from THP-1 cells, and examined how...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Chuan, Luo, Shao-Jian, Fan, Wu, Zhou, Tian-Li, Tan, Dan-Qin, Tan, Rong-Xiong, Xian, Qun-Ze, Li, Jian, Huang, Chun-Ming, Wang, Mao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433570/
https://www.ncbi.nlm.nih.gov/pubmed/36059551
http://dx.doi.org/10.3389/fimmu.2022.922173