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Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
Transposable elements (TEs) are widespread genetic parasites known to be kept under tight transcriptional control. Here, we describe a functional connection between the mouse-orthologous “nuclear exosome targeting” (NEXT) and “human silencing hub” (HUSH) complexes, involved in nuclear RNA decay and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433625/ https://www.ncbi.nlm.nih.gov/pubmed/35349793 http://dx.doi.org/10.1016/j.molcel.2022.03.004 |