Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases

Renal cell carcinoma (RCC) occurs in a number of cancer predisposition syndromes, but the genetic architecture of susceptibility to RCC is not well defined. We investigated the frequency of pathogenic and likely pathogenic (P/LP) germline variants in cancer susceptibility genes (CSGs) within a large...

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Detalles Bibliográficos
Autores principales: Yngvadottir, Bryndis, Andreou, Avgi, Bassaganyas, Laia, Larionov, Alexey, Cornish, Alex J, Chubb, Daniel, Saunders, Charlie N, Smith, Philip S, Zhang, Huairen, Cole, Yasemin, Research Consortium, Genomics England, Larkin, James, Browning, Lisa, Turajlic, Samra, Litchfield, Kevin, Houlston, Richard S, Maher, Eamonn R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433729/
https://www.ncbi.nlm.nih.gov/pubmed/35441217
http://dx.doi.org/10.1093/hmg/ddac089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433729/
https://www.ncbi.nlm.nih.gov/pubmed/35441217
http://dx.doi.org/10.1093/hmg/ddac089

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