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Methamphetamine induces transcriptional changes in cultured HIV-infected mature monocytes that may contribute to HIV neuropathogenesis

HIV-associated neurocognitive impairment (HIV-NCI) persists in 15-40% of people with HIV (PWH) despite effective antiretroviral therapy. HIV-NCI significantly impacts quality of life, and there is currently no effective treatment for it. The development of HIV-NCI is complex and is mediated, in part...

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Detalles Bibliográficos
Autores principales: Chilunda, Vanessa, Weiselberg, Jessica, Martinez-Meza, Samuel, Mhamilawa, Lwidiko E., Cheney, Laura, Berman, Joan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433802/
https://www.ncbi.nlm.nih.gov/pubmed/36059515
http://dx.doi.org/10.3389/fimmu.2022.952183