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Assessment of disease activity in patients with rheumatoid arthritis using plasma tumour M2-pyruvate kinase test
BACKGROUND: Pyruvate kinase M2 (PKM2) is an enzyme that regulates the final process of glycolysis and exists in tetrameric and dimeric forms. The dimeric form of PKM2, also known as tumour M2-PK, increases when aerobic glycolysis is augmented, a feature observed in rheumatoid arthritis (RA). We inve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433835/ https://www.ncbi.nlm.nih.gov/pubmed/36059477 http://dx.doi.org/10.3389/fimmu.2022.901555 |