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Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome

Primary immunodeficiency diseases (PIDs) are a group of rare inherited disorders affecting the immune system that can be conventionally treated with allogeneic hematopoietic stem cell transplantation and with experimental autologous gene therapy. With both approaches still facing important challenge...

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Detalles Bibliográficos
Autores principales: Naseem, Asma, Steinberg, Zohar, Cavazza, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433875/
https://www.ncbi.nlm.nih.gov/pubmed/36059471
http://dx.doi.org/10.3389/fimmu.2022.966084