Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling

Strategies based on intracellular expression of artificial binding domains present several advantages over manipulating nucleic acid expression or the use of small molecule inhibitors. Intracellularly-functional nanobodies can be considered as promising macrodrugs to study key signaling pathways by...

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Detalles Bibliográficos
Autores principales: Keller, Laura, Tardy, Claudine, Ligat, Laetitia, Le Pennec, Soazig, Bery, Nicolas, Koraïchi, Faten, Chinestra, Patrick, David, Mélissa, Gence, Rémi, Favre, Gilles, Cabantous, Stéphanie, Olichon, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433928/
https://www.ncbi.nlm.nih.gov/pubmed/36059552
http://dx.doi.org/10.3389/fimmu.2022.980539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433928/
https://www.ncbi.nlm.nih.gov/pubmed/36059552
http://dx.doi.org/10.3389/fimmu.2022.980539

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