Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets

Organoids enable in vitro modeling of complex developmental processes and disease pathologies. Like most 3D cultures, organoids lack sufficient oxygen supply and therefore experience cellular stress. These negative effects are particularly prominent in complex models, such as brain organoids, and ca...

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Detalles Bibliográficos
Autores principales: Vértesy, Ábel, Eichmüller, Oliver L, Naas, Julia, Novatchkova, Maria, Esk, Christopher, Balmaña, Meritxell, Ladstaetter, Sabrina, Bock, Christoph, von Haeseler, Arndt, Knoblich, Juergen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433936/
https://www.ncbi.nlm.nih.gov/pubmed/35919947
http://dx.doi.org/10.15252/embj.2022111118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433936/
https://www.ncbi.nlm.nih.gov/pubmed/35919947
http://dx.doi.org/10.15252/embj.2022111118

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