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Dose- and Volume-Limiting Late Toxicity of FLASH Radiotherapy in Cats with Squamous Cell Carcinoma of the Nasal Planum and in Mini Pigs

PURPOSE: The FLASH effect is characterized by normal tissue sparing without compromising tumor control. Although demonstrated in various preclinical models, safe translation of FLASH-radiotherapy stands to benefit from larger vertebrate animal models. Based on prior results, we designed a randomized...

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Detalles Bibliográficos
Autores principales: Rohrer Bley, Carla, Wolf, Friederike, Gonçalves Jorge, Patrik, Grilj, Veljko, Petridis, Ioannis, Petit, Benoit, Böhlen, Till T., Moeckli, Raphael, Limoli, Charles, Bourhis, Jean, Meier, Valeria, Vozenin, Marie-Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433962/
https://www.ncbi.nlm.nih.gov/pubmed/35421221
http://dx.doi.org/10.1158/1078-0432.CCR-22-0262