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Quantitative susceptibility mapping of basal ganglia iron is associated with cognitive and motor functions that distinguish spinocerebellar ataxia type 6 and type 3

BACKGROUND: In spinocerebellar ataxia type 3 (SCA3), volume loss has been reported in the basal ganglia, an iron-rich brain region, but iron content has not been examined. Recent studies have reported that patients with SCA6 have markedly decreased iron content in the cerebellar dentate, coupled wit...

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Detalles Bibliográficos
Autores principales: Marvel, Cherie L., Chen, Lin, Joyce, Michelle R., Morgan, Owen P., Iannuzzelli, Katherine G., LaConte, Stephen M., Lisinski, Jonathan M., Rosenthal, Liana S., Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433989/
https://www.ncbi.nlm.nih.gov/pubmed/36061587
http://dx.doi.org/10.3389/fnins.2022.919765