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The prion-like transmission of tau oligomers via exosomes

The conversion and transmission of misfolded proteins established the basis for the prion concept. Neurodegenerative diseases are considered “prion-like” disorders that lack infectivity. Among them, tauopathies are characterized by the conversion of native tau protein into an abnormally folded aggre...

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Detalles Bibliográficos
Autores principales: Jackson, Noel A., Guerrero-Muñoz, Marcos J., Castillo-Carranza, Diana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434014/
https://www.ncbi.nlm.nih.gov/pubmed/36062141
http://dx.doi.org/10.3389/fnagi.2022.974414