Feeding activates FGF15‐SHP‐TFEB‐mediated lipophagy in the gut

Lysosome‐mediated macroautophagy, including lipophagy, is activated under nutrient deprivation but is repressed after feeding. We show that, unexpectedly, feeding activates intestinal autophagy/lipophagy in a manner dependent on both the orphan nuclear receptor, small heterodimer partner (SHP/NR0B2)...

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Detalles Bibliográficos
Autores principales: Seok, Sunmi, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434102/
https://www.ncbi.nlm.nih.gov/pubmed/35686465
http://dx.doi.org/10.15252/embj.2021109997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434102/
https://www.ncbi.nlm.nih.gov/pubmed/35686465
http://dx.doi.org/10.15252/embj.2021109997

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