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Feeding activates FGF15‐SHP‐TFEB‐mediated lipophagy in the gut
Lysosome‐mediated macroautophagy, including lipophagy, is activated under nutrient deprivation but is repressed after feeding. We show that, unexpectedly, feeding activates intestinal autophagy/lipophagy in a manner dependent on both the orphan nuclear receptor, small heterodimer partner (SHP/NR0B2)...
Autores principales: | Seok, Sunmi, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434102/ https://www.ncbi.nlm.nih.gov/pubmed/35686465 http://dx.doi.org/10.15252/embj.2021109997 |
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