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Senescence of alveolar epithelial cells impacts initiation and chronic phases of murine fibrosing interstitial lung disease

Fibrosing interstitial lung disease (ILD) develops due to the impaired reparative processes following lung tissue damage. Cellular senescence has been reported to contribute to the progression of fibrosis. However, the mechanisms by which these senescent cells initiate and/or drive the progression o...

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Detalles Bibliográficos
Autores principales: Yamada, Zento, Nishio, Junko, Motomura, Kaori, Mizutani, Satoshi, Yamada, Soichi, Mikami, Tetuo, Nanki, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434111/
https://www.ncbi.nlm.nih.gov/pubmed/36059455
http://dx.doi.org/10.3389/fimmu.2022.935114