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An integrative pan-cancer analysis revealing the difference in small ring finger family of SCF E3 ubiquitin ligases

BACKGROUND: The SCF (Skp1-cullin-F-box proteins) complex is the largest family of E3 ubiquitin ligases that mediate multiple specific substrate proteins degradation. Two ring-finger family members RBX1/ROC1 and RBX2/RNF7/SAG are small molecular proteins necessary for ubiquitin ligation activity of t...

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Detalles Bibliográficos
Autores principales: Huang, Tingting, Li, Jiwei, Liu, Xinli, Shi, Bingbing, Li, Shiqin, An, Han-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434121/
https://www.ncbi.nlm.nih.gov/pubmed/36059474
http://dx.doi.org/10.3389/fimmu.2022.968777